Description

3'-Desamino-3'-Dimethylformamidinedoxorubicin is a chemically modified derivative of the potent anthracycline antibiotic, doxorubicin, designed to explore structure-activity relationships and potentially improve therapeutic profiles. This compound is a critical research-grade intermediate for pharmaceutical development, particularly in the study of anticancer agents and their mechanisms of action. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in oncology drug discovery and development.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate in the exploration of novel anthracycline-based chemotherapeutic agents.
• Oncology Drug Discovery: Used in biological assays to study the impact of structural modifications on cytotoxicity, DNA intercalation, and topoisomerase II inhibition.
• Mechanistic Studies: Serves as a reference standard or probe compound for investigating the pharmacokinetics, metabolism, and resistance mechanisms of anthracycline drugs.
• Academic Research: Employed in university and institutional labs for chemical biology and medicinal chemistry projects focused on anticancer drug design.
• Biochemical Reagent: May be used in specialized in vitro studies to understand cellular apoptosis pathways and drug-target interactions.

Basic Information

Product Name	3'-Desamino-3'-Dimethylformamidinedoxorubicin
CAS No.	119864-31-2
Molecular Formula	C29H33NO12
Molecular Weight	587.57 g/mol
Synonyms	3'-Desamino-3'-(N,N-dimethylformamidino)doxorubicin; 3'-Deamino-3'-dimethylformamidinedoxorubicin; Doxorubicin, 3'-desamino-3'-(N,N-dimethylformamidino)-; 3'-Desamino-3'-(dimethylformamidino)doxorubicin; 3'-Deamino-3'-(dimethylformamidino)doxorubicin; 3'-Desamino-3'-dimethylformamidinodoxorubicin; 3'-Deamino-3'-dimethylformamidinodoxorubicin; 119864-31-2
EINECS	Contact for details

Quality Control

Our 3'-Desamino-3'-Dimethylformamidinedoxorubicin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to industry-standard analytical methods to guarantee the material meets the precise requirements of advanced pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or Certificate of Analysis. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.