Description

2-Fluoro-6-(2,2,2-trifluoroethoxy)benzonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced chemical synthesis. Its unique molecular structure, featuring both fluorine and a trifluoroethoxy substituent, makes it a critical intermediate for developing novel active compounds with enhanced properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for CNS and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms contribute to metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials.
• Cross-Coupling Reactions: The nitrile and halogen groups make it a versatile substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed couplings.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	2-Fluoro-6-(2,2,2-trifluoroethoxy)benzonitrile
CAS No.	119584-74-6
Molecular Formula	C9H5F4NO
Molecular Weight	219.14 g/mol
Synonyms	2-Fluoro-6-(2,2,2-trifluoroethoxy)benzonitrile; 2-Fluoro-6-(trifluoroethoxy)benzonitrile; 2-Fluoro-α,α,α-trifluoro-p-cresol cyanide (related); Benzonitrile, 2-fluoro-6-(2,2,2-trifluoroethoxy)-; 119584-74-6; 2-F-6-TFEO-BN; 6-Cyano-3-fluoro-1-(trifluoroethoxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(2,2,2-trifluoroethoxy)benzonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom purity grades can be discussed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.