Description

2-Fluoro-6-(Methylthio)Benzonitrile is a versatile fluorinated aromatic nitrile building block, distinguished by its unique combination of fluorine and methylthio substituents. This compound is highly valued in advanced organic synthesis for its ability to introduce specific steric and electronic properties into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorine and sulfur motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of advanced polymers and liquid crystals where the benzonitrile core contributes to thermal stability and mesomorphic properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	2-Fluoro-6-(Methylthio)Benzonitrile
CAS No.	119584-71-3
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	2-Fluoro-6-(methylsulfanyl)benzonitrile; 2-Fluoro-6-methylthiobenzonitrile; 6-Fluoro-2-(methylthio)benzonitrile; Benzonitrile, 2-fluoro-6-(methylthio)-; 2-Fluoro-6-methylmercaptobenzonitrile; 2-Fluoro-6-(methylmercapto)benzonitrile; 2-Fluoro-6-(methylsulfanyl)benzonitrile; 2-Fluoro-6-(methylthio)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Methylthio)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.