Description

4,5-Dimethoxy-2-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring methoxy and fluorine substituents, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, CNS-active compounds, and other fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands for catalysis, and specialty chemicals with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4,5-Dimethoxy-2-Fluorobenzonitrile
CAS No.	119396-88-2
Molecular Formula	C9H8FNO2
Molecular Weight	181.16 g/mol
Synonyms	2-Fluoro-4,5-dimethoxybenzonitrile; 4,5-Dimethoxy-2-fluorobenzonitrile; Benzonitrile, 2-fluoro-4,5-dimethoxy-; 2-Fluoro-4,5-dimethoxybenzonitrile; 4,5-Dimethoxy-2-fluorobenzonitrile; 119396-88-2 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 4,5-Dimethoxy-2-Fluorobenzonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.