Description

2-Amino-2-(3-Fluorophenyl)Acetonitrile is a versatile fluorinated nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and a nitrile group on a fluorinated aromatic scaffold, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries. It serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex fluorinated aromatic compounds for material science and electronic chemicals.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2-Amino-2-(3-Fluorophenyl)Acetonitrile
CAS No.	118880-96-9
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	2-Amino-2-(3-fluorophenyl)acetonitrile; (3-Fluorophenyl)glycinonitrile; 3-Fluoro-α-aminobenzeneacetonitrile; α-Amino-3-fluorobenzeneacetonitrile; 2-Amino-2-(m-fluorophenyl)acetonitrile; (3-Fluorophenyl)(cyano)methanamine; 118880-96-9; m-Fluorophenylglycinonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-2-(3-Fluorophenyl)Acetonitrile is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure high purity and consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.