Description

Cyclopentanemethanol, 3-Amino-1-Fluoro-4-Hydroxy-, (1Alpha,3Beta,4Alpha)- (9Ci) is a high-purity, multifunctional chiral building block of significant interest in advanced organic synthesis. Its unique stereochemistry and functional group array make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where its specific stereochemistry can influence biological activity and environmental selectivity.
• Organofluorine Chemistry: Acts as a valuable precursor for introducing fluorine atoms into complex molecules, leveraging the fluorine atom's ability to modulate bioavailability, metabolic stability, and binding affinity.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and methodologies for stereoselective synthesis.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: A critical material for university and government laboratories conducting fundamental research in synthetic organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Cyclopentanemethanol, 3-Amino-1-Fluoro-4-Hydroxy-, (1Alpha,3Beta,4Alpha)- (9Ci)
CAS No.	118189-49-4
Molecular Formula	C7H12FNO2
Molecular Weight	161.17 g/mol
Synonyms	(1α,3β,4α)-3-Amino-1-fluoro-4-hydroxycyclopentanemethanol; 3-Amino-1-fluoro-4-hydroxycyclopentanemethanol (1α,3β,4α)-; 1-Fluoro-3-amino-4-hydroxycyclopentanemethanol; (1R,3S,4R)-3-Amino-1-fluoro-4-(hydroxymethyl)cyclopentanol; Aminofluorohydroxycyclopentanemethanol; CAS 118189-49-4; (1α,3β,4α)-Aminofluorohydroxycyclopentanemethanol
EINECS	Contact for details

Quality Control

Our Cyclopentanemethanol, 3-Amino-1-Fluoro-4-Hydroxy-, (1Alpha,3Beta,4Alpha)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.