Description

(+)-Tertatolol CAS NO 117305-34-7 is a high-purity enantiomer of the potent non-selective β-adrenergic receptor antagonist, tertatolol. This compound is of significant value in pharmaceutical research and development, particularly for studying stereospecific drug-receptor interactions and metabolic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular drug discovery, pharmacokinetic studies, and the synthesis of novel chiral active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for analytical method development, validation, and quality control in API manufacturing.
• Cardiovascular Research: Used as a key pharmacological tool to investigate β-blocker mechanisms, receptor binding affinity, and stereoselectivity in preclinical studies.
• Metabolite Synthesis & Identification: Employed as a precursor or standard in the synthesis and characterization of specific drug metabolites for safety and efficacy profiling.
• Chiral Chemistry Studies: Essential for research focusing on the differential biological activity, pharmacokinetics, and toxicity of individual enantiomers.
• Formulation Development: Used in early-stage development of enantiomerically pure drug formulations to assess stability and bioavailability.

Basic Information

Product Name	(+)-Tertatolol
CAS No.	117305-34-7
Molecular Formula	C20H25NO3S
Molecular Weight	359.48 g/mol
Synonyms	(+)-Tertatolol; (S)-Tertatolol; (S)-1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepin-2-yl)oxy]propan-2-ol; (S)-1-(tert-Butylamino)-3-[(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)oxy]-2-propanol; Levotertatolol; S-(-)-Tertatolol; Tertatolol enantiomer; S-Tertatolol
EINECS	Contact for details

Quality Control

Our (+)-Tertatolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet exacting standards for research applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.