Description

Cyclopentanecarboxylic Acid, 1-Fluoro-, Ethyl Ester (9Ci) is a high-purity fluorinated organic building block with the CAS number 116816-10-5. This compound is valued for its unique structure, which incorporates both a cyclopentane ring and a fluorine atom, making it a versatile intermediate for introducing conformational constraints and fluorinated motifs into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and lead optimization.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Fluorine Chemistry Research: Serves as a valuable model compound and starting material in academic and industrial laboratories studying fluorination effects and reaction mechanisms.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and liquid crystals, where the fluorinated cyclopentane unit can modify physical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated scaffolds.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 1-Fluoro-, Ethyl Ester (9Ci)
CAS No.	116816-10-5
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	Ethyl 1-Fluorocyclopentanecarboxylate; 1-Fluorocyclopentanecarboxylic Acid Ethyl Ester; Ethyl 1-Fluorocyclopentane-1-carboxylate; 1-Fluoro-1-(ethoxycarbonyl)cyclopentane; Cyclopentanecarboxylic acid, 1-fluoro-, ethyl ester; 116816-10-5; 1-Fluorocyclopentane-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 1-Fluoro-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC/HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.