Description

(-)-Tertatolol CAS NO 116127-10-7 is a high-purity, enantiomerically pure β-adrenergic receptor antagonist (β-blocker). This compound is a critical chiral intermediate and reference standard in pharmaceutical research and development, valued for its stereospecific biological activity. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in cardiovascular drug discovery, metabolic studies, and the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical R&D Intermediate: A key chiral building block for the synthesis of novel β-blocker drugs and related therapeutic agents.
• Biochemical Research: Used as a selective ligand in receptor binding assays and pharmacological studies to investigate β-adrenergic pathways.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Metabolic Studies: Employed in preclinical research to study drug metabolism, pharmacokinetics, and stereoselective enzymatic interactions.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in medicinal chemistry and pharmacology.

Basic Information

Product Name	(-)-Tertatolol
CAS No.	116127-10-7
Molecular Formula	C₂₀H₂₅NO₃S
Molecular Weight	359.48 g/mol
Synonyms	(-)-Tertatolol; (S)-Tertatolol; Levotertatolol; 1-[(1,1-Dimethylethyl)amino]-3-[(2-methyl-4-thiazolyl)oxy]-2-propanol; (S)-1-(tert-Butylamino)-3-(2-methyl-1,3-thiazol-4-yloxy)propan-2-ol; Tertatolol S-(-)-enantiomer; S-(-)-Tertatolol
EINECS	Contact for details

Quality Control

Our (-)-Tertatolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.