Description

Pyridine,3-(1,1-Difluoroethyl)-(9Ci) CAS NO 114468-03-0 is a specialized fluorinated pyridine derivative, a high-value building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroethyl group, enabling precise molecular modifications that are difficult to achieve with other reagents. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where the introduction of fluorine atoms is critical for enhancing metabolic stability, bioavailability, or binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Active Ingredient Development: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating sophisticated nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new C-F bond formation reactions and the properties of fluorinated heterocycles.

Basic Information

Product Name	Pyridine,3-(1,1-Difluoroethyl)-(9Ci)
CAS No.	114468-03-0
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	3-(1,1-Difluoroethyl)pyridine; 1-(3-Pyridyl)-1,1-difluoroethane; 3-(Difluoroethyl)pyridine; 1,1-Difluoro-1-(3-pyridyl)ethane; 3-(1,1-Difluoroethyl)pyridine (9CI); Pyridine, 3-(1,1-difluoroethyl)-; 114468-03-0
EINECS	Contact for details

Quality Control

Our Pyridine,3-(1,1-Difluoroethyl)-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specified requirements. Our quality system supports development and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.