Description

3-Methoxy-2,4,5-Trifluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique trifluoromethyl and methoxy substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science.
• Custom Synthesis: Used by fine chemical manufacturers for contract synthesis and the production of specialized fluorinated compounds.

Basic Information

Product Name	3-Methoxy-2,4,5-Trifluorobenzonitrile
CAS No.	112811-63-9
Molecular Formula	C8H4F3NO
Molecular Weight	195.12 g/mol
Synonyms	2,4,5-Trifluoro-3-methoxybenzonitrile; Benzonitrile, 2,4,5-trifluoro-3-methoxy-; 3-Methoxy-2,4,5-trifluorobenzene carbonitrile; 2,4,5-Trifluoro-3-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Methoxy-2,4,5-Trifluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.