Description

10-o-Rhodosaminyl β-Rhodomycinone is a specialized anthracycline derivative and a key structural component of certain rhodomycin antibiotics. This compound matters as a critical intermediate and reference standard in the research and development of novel antitumor agents and antibiotics. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology drug discovery and microbial metabolite synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the semi-synthesis of complex anthracycline-based chemotherapeutic agents.
• Biochemical Research: Used as a reference standard and probe in studies investigating the biosynthesis, structure-activity relationships (SAR), and mode of action of rhodomycin-class antibiotics.
• Anticancer Drug Discovery: Acts as a core scaffold for the design and development of new analogs with potential improved efficacy or reduced cardiotoxicity.
• Microbiology Studies: Employed in research on Streptomyces and other actinobacteria to understand the genetic regulation of secondary metabolite production.
• Analytical Standard: Provides a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.

Basic Information

Product Name	10-o-Rhodosaminyl β-Rhodomycinone
CAS No.	112680-26-9
Molecular Formula	C32H37NO12
Molecular Weight	627.64 g/mol
Synonyms	10-O-Rhodosaminyl-β-rhodomycinone; β-Rhodomycinone 10-O-rhodosaminide; 10-Deoxy-ε-rhodomycinone; 10-O-(2,6-Dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-β-rhodomycinone; 7,9,11-Trihydroxy-10-[(2S,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-8-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-2-carbaldehyde; Aclacinomycin A aglycone precursor; Anthracycline intermediate
EINECS	Contact for details

Quality Control

Our 10-o-Rhodosaminyl β-Rhodomycinone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Red to reddish-brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.