Description

2-Methyl-6-Nitrobenzotrifluoride is a specialized fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the combination of a nitro group and a trifluoromethyl group on a methyl-substituted benzene ring, enabling precise chemical transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity building blocks for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated aromatic units.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where nitro and trifluoromethyl groups modify color properties and lightfastness.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct more complex biaryl structures for various applications.

Basic Information

Product Name	2-Methyl-6-Nitrobenzotrifluoride
CAS No.	112641-21-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	1-Methyl-2-nitro-3-(trifluoromethyl)benzene; 2-Nitro-α,α,α-trifluoro-m-xylene; 3-(Trifluoromethyl)-2-nitrotoluene; 2-Methyl-6-nitrobenzotrifluoride; 2-Nitro-6-methylbenzotrifluoride; 6-Methyl-2-nitrobenzotrifluoride; m-Xylene, 2-nitro-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.