Description

3-(Fluoromethyl)Phosphoenolpyruvate is a high-value, fluorinated analog of phosphoenolpyruvate (PEP), a critical intermediate in biochemical pathways. This compound matters for its role as a specialized building block in the synthesis of novel fluorinated pharmaceuticals and biochemical probes, where the introduction of fluorine can dramatically alter metabolic stability, bioavailability, and binding affinity. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, enzyme mechanism studies, and the development of positron emission tomography (PET) tracers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated nucleoside analogs and other bioactive molecules targeting viral infections and cancers.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases and enzymes in the glycolytic pathway, to investigate metabolic regulation.
• PET Tracer Development: Serves as a starting material for synthesizing fluorine-18 labeled compounds used in medical imaging diagnostics.
• Proteomics & Chemical Biology: Employed in the design of activity-based probes to label and study specific enzyme families in complex biological systems.
• Agrochemical Research: Potential intermediate for developing new fluorinated plant growth regulators or herbicides with enhanced properties.

Basic Information

Product Name	3-(Fluoromethyl)Phosphoenolpyruvate
CAS No.	112505-10-9
Molecular Formula	C4H6FO7P
Molecular Weight	216.06 g/mol
Synonyms	3-(Fluoromethyl)-2-(phosphonooxy)-2-propenoic acid; (Fluoromethyl)phosphoenolpyruvic acid; PEP-F; Fluoromethyl-PEP; 2-(Fluoromethyl)-2-(phosphonooxy)acrylic acid; Phosphoenol-3-(fluoromethyl)pyruvate; 3-Fluoromethylphosphoenolpyruvate
EINECS	Contact for details

Quality Control

Our 3-(Fluoromethyl)Phosphoenolpyruvate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards, and material can be supplied to meet specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic and moisture-sensitive nature, the container should be allowed to reach room temperature before opening to prevent condensation and hydrolysis. Handle in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (H-NMR)	Conforms to structure
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.