Description

6-α-Hydroxy Dexamethasone is a key pharmaceutical intermediate and a hydroxylated derivative of the potent glucocorticoid dexamethasone. This compound is of significant interest for its role in the research and synthesis of novel steroid-based therapeutics. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of advanced corticosteroid analogs and metabolic studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel corticosteroid drugs and their metabolites.
• Research Chemical: Used in biochemical and pharmacological research to study steroid metabolism and receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Metabolite Studies: Employed in the investigation of dexamethasone metabolic pathways and the activity of its derivatives.

Basic Information

Product Name	6-α-Hydroxy Dexamethasone
CAS No.	111897-35-9
Molecular Formula	C22H29FO6
Molecular Weight	408.46 g/mol
Synonyms	6α-Hydroxydexamethasone; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 6α-ol; (6α,11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-6-ol; Dexamethasone 6α-ol; 6α-Hydroxy Dexamethasone
EINECS	Contact for details

Quality Control

Our 6-α-Hydroxy Dexamethasone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.