Description

Anguinomycin A CAS NO 111278-01-4 is a potent and selective natural product inhibitor of mitochondrial complex I, exhibiting significant biological activity. This compound is a critical research tool for studying cellular metabolism, apoptosis, and signal transduction pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in oncology, metabolic disease, and fundamental biochemical research.

Application

• Biochemical Research: A key tool for investigating mitochondrial function, oxidative phosphorylation, and energy metabolism in cell biology studies.
• Oncology Research: Used in preclinical studies to explore its effects on cancer cell proliferation, survival, and as a potential lead compound for anticancer drug discovery.
• Metabolic Disease Models: Applied in research focused on diseases related to mitochondrial dysfunction, such as neurodegenerative disorders and diabetes.
• Apoptosis Induction Studies: Employed to study programmed cell death mechanisms and screen for compounds that modulate apoptotic pathways.
• Signal Transduction Analysis: Serves as a probe to dissect cellular signaling networks affected by changes in mitochondrial activity and ATP production.
• High-Throughput Screening (HTS): Used as a reference standard or active control in assays designed to identify novel modulators of mitochondrial complex I.

Basic Information

Product Name	Anguinomycin A
CAS No.	111278-01-4
Molecular Formula	C34H44O8
Molecular Weight	580.71 g/mol
Synonyms	Anguinomycin A; 111278-01-4; Anguinomycin; (-)-Anguinomycin A; Anguinomycin A, (-)-; (3S,4S,5S,6S,7R,8R,9S,10R,11S,12S,13S,14R,15R,16S,17S,18S,19S,20S,21S,22R,23S,24S,25S,26S,27S,28S,29S,30S,31S,32S,33S,34S)-34-Hydroxy-4,6,8,10,12,14,16,18,20,22,24,26,28,30,32-pentadecamethyl-3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33-hexadecaoxodotriacontane-1,2-dione
EINECS	Contact for details

Quality Control

Our Anguinomycin A is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation, NMR and MS for structural identity, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards. We support custom synthesis and purification to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.