Description

Tetramethylammonium Fluoride Trihydrate is a versatile and highly reactive fluoride source and phase-transfer catalyst. This compound is critical for facilitating challenging nucleophilic fluorination reactions and other synthetic transformations in controlled environments. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds and fine chemicals.

Application

• Nucleophilic Fluorination Agent: A key reagent for introducing fluorine atoms into organic molecules in pharmaceutical and agrochemical synthesis.
• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, improving yield and efficiency in organic synthesis.
• Electrolyte Additive: Used in specialized electrochemical applications and battery research.
• Etching & Surface Modification: Employed in microfabrication and surface treatment processes for semiconductors and advanced materials.
• Research & Development: Serves as a fundamental tool in academic and industrial R&D for exploring new fluorination methodologies.
• Precursor for Fluorinating Reagents: Used in the preparation of other, more complex fluorination agents.

Basic Information

Product Name	Tetramethylammonium Fluoride Trihydrate
CAS No.	111203-44-2
Molecular Formula	C4H12FNO3 or (CH3)4N·F·3H2O
Molecular Weight	147.15 g/mol
Synonyms	TMAF Trihydrate; Tetramethylammonium Fluoride Hydrate; N,N,N-Trimethylmethanaminium Fluoride Trihydrate; Ammonium, tetramethyl-, fluoride, trihydrate; Fluorotetramethylammonium Trihydrate; TMAF·3H2O; (CH3)4NF·3H2O
EINECS	Contact for details

Quality Control

Our Tetramethylammonium Fluoride Trihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay, water content, and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place, ideally at 2-8°C. The container should be kept tightly sealed under an inert atmosphere (e.g., argon or nitrogen) when not in use to prevent degradation and moisture absorption. Keep away from strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms
Assay (TMAF·3H2O)	≥ 98.0 %
Water Content (KF)	30.0 - 36.0 %
Fluoride Content	12.0 - 13.5 %
Heavy Metals (as Pb)	≤ 10 ppm
Chloride (Cl)	≤ 0.1 %
Sulfate (SO4)	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.