Description

4,4,4-Trifluoro-1-(2-Fluorophenyl)Butane-1,3-Dione is a high-purity fluorinated diketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique fluorine-substituted structure imparts desirable properties like metabolic stability and enhanced lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocycles and active molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel fluorinated pesticides and herbicides, where fluorine atoms can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for β-diketonate ligands used in coordination chemistry and catalysis, especially for lanthanide and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for advanced materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex, value-added chemical entities in academic and industrial labs.

Basic Information

Item	Details
Product Name	4,4,4-Trifluoro-1-(2-Fluorophenyl)Butane-1,3-Dione
CAS No.	111102-82-0
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	1-(2-Fluorophenyl)-4,4,4-trifluorobutane-1,3-dione; 2-Fluorophenyl 4,4,4-trifluoroacetoacetate; 4,4,4-Trifluoro-1-(2-fluorophenyl)-1,3-butanedione; 2-Fluorobenzoyltrifluoroacetone; 2-FBTA; TFBD; α-Fluorobenzoyltrifluoroacetone
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-(2-Fluorophenyl)Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.