Description

Noberastine is a high-purity pharmaceutical intermediate and active ingredient with the CAS registry number 110588-56-2. This compound is of significant commercial importance for its role in the synthesis of advanced pharmaceutical agents, particularly in the respiratory and anti-allergy therapeutic segments. It is primarily required by manufacturers in the pharmaceutical and fine chemical industries for research, development, and large-scale production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antihistamine and respiratory drugs.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for formulating new therapeutic compounds targeting allergic conditions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecules.
• Biochemical Research: Serves as a reference standard and reagent in pharmacological and biochemical studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
• Generic Drug Manufacturing: Utilized in the production of generic versions of established allergy medications.

Basic Information

Product Name	Noberastine
CAS No.	110588-56-2
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Noberastine; 110588-56-2; 2-[4-(Diphenylmethoxy)-1-piperidinyl]ethyl 1H-benzimidazole-2-carboxylate; Ebastel; Ebastine Impurity; Ebastine Related Compound; Kestine Impurity; LAS-W 090
EINECS	Contact for details

Quality Control

Our Noberastine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality documentation, including Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. The product is suitable for use under cGMP guidelines for pharmaceutical manufacturing, and specifications can be aligned with USP/EP monograph requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.