Description

2-Cyclohexen-1-One, 2-Fluoro-3-Hydroxy-5,5-Dimethyl- is a fluorinated cyclic enone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive α,β-unsaturated ketone adjacent to fluorine and hydroxyl substituents, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated cyclohexenone core contributes to biological activity.
• Advanced Material Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological mechanisms and enzyme interactions.
• Asymmetric Catalysis Substrate: Utilized as a test substrate in the development of new chiral catalysts and methodologies due to its multiple functional handles.
• Flavor & Fragrance Chemistry: Investigated for the synthesis of novel aroma chemicals and flavoring agents with complex, modified terpene-like structures.

Basic Information

Product Name	2-Cyclohexen-1-One, 2-Fluoro-3-Hydroxy-5,5-Dimethyl-
CAS No.	109801-21-0
Molecular Formula	C8H11FO2
Molecular Weight	158.17 g/mol
Synonyms	2-Fluoro-3-hydroxy-5,5-dimethylcyclohex-2-en-1-one; 5,5-Dimethyl-2-fluoro-3-hydroxy-2-cyclohexen-1-one; 3-Hydroxy-2-fluoro-5,5-dimethyl-2-cyclohexen-1-one; 2-Fluoro-5,5-dimethyl-3-hydroxy-2-cyclohexenone; Fluorinated Dimethyl Cyclohexenone; 109801-21-0; 2-Cyclohexen-1-one, 2-fluoro-3-hydroxy-5,5-dimethyl-
EINECS	Contact for details

Quality Control

Our 2-Cyclohexen-1-One, 2-Fluoro-3-Hydroxy-5,5-Dimethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.