Description

4-o-Daunosaminyl-2,4,5,12-Tetrahydroxy-2-(2-Methylpropanoyl)-1,2,3,4-Tetrahydro-6,11-Naphthacenedione is a structurally complex anthracycline derivative of significant interest in advanced pharmaceutical research and development. Its core value lies in its potential as a key synthetic intermediate or reference standard for novel chemotherapeutic agents, particularly in the exploration of next-generation cancer treatments. This compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on oncology drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: Serves as a critical high-purity standard for the qualitative and quantitative analysis (HPLC, LC-MS) of anthracycline-based APIs and related compounds.
• Oncology Drug Discovery Intermediate: Used as a sophisticated building block in the research and synthesis of novel anthracycline analogs with potentially improved efficacy or reduced side-effect profiles.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR), mechanism of action, and metabolic pathways of daunorubicin and doxorubicin derivatives.
• Academic & Contract Research: Utilized by universities and CROs (Contract Research Organizations) for fundamental chemical and pharmacological research projects.
• Process Development & Scale-up: Acts as a benchmark compound during the optimization and validation of synthetic routes for complex pharmaceutical molecules.

Basic Information

Product Name	4-o-Daunosaminyl-2,4,5,12-Tetrahydroxy-2-(2-Methylpropanoyl)-1,2,3,4-Tetrahydro-6,11-Naphthacenedione
CAS No.	109485-65-6
Molecular Formula	C30H35NO11
Molecular Weight	585.60 g/mol
Synonyms	4'-O-Daunosaminyldoxorubicinone; 4'-O-Daunosaminyl-2,4,5,12-tetrahydroxy-2-(2-methylpropanoyl)-1,2,3,4-tetrahydro-6,11-naphthacenedione; 4'-O-Daunosaminyl Adriamycinone; 4'-O-Daunosaminyl Doxorubicinone; 4'-O-Daunosaminyl-2,4,5,12-tetrahydroxy-2-(2-methylpropanoyl)-1,2,3,4-tetrahydro-6,11-naphthacenedione; 4'-O-Daunosaminyl-2,4,5,12-tetrahydroxy-2-(2-methylpropanoyl)-1,2,3,4-tetrahydro-6,11-naphthacenedione (CAS 109485-65-6); 4'-O-Daunosaminyl-2,4,5,12-tetrahydroxy-2-(2-methylpropanoyl)-1,2,3,4-tetrahydro-6,11-naphthacenedione (Doxorubicinone derivative)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as assay, related substances, and residual solvents are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.