Description

4-Pregnene-17A,20B-Diol-3-One 20-*Acetat E CAS NO 108448-27-7 is a high-purity steroid intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key building block in the production of complex steroid-based active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development and production of corticosteroids and other specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent corticosteroid APIs.
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-based drug candidates.
• Process Chemistry: Serves as a standardized starting material for optimizing scalable and cost-effective manufacturing routes for target molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	4-Pregnene-17A,20B-Diol-3-One 20-*Acetat E
CAS No.	108448-27-7
Molecular Formula	C23H34O4
Molecular Weight	374.52 g/mol
Synonyms	17α,20β-Dihydroxypregn-4-en-3-one 20-acetate; 20β-Acetoxy-17α-hydroxypregn-4-en-3-one; Pregna-4-ene-3-one, 17,20-diol, 20-acetate, (17α,20β)-; 17α-Hydroxy-20β-acetoxypregn-4-en-3-one; 108448-27-7; (17α,20β)-17,20-Dihydroxypregn-4-en-3-one 20-acetate
EINECS	Contact for details

Quality Control

Our 4-Pregnene-17A,20B-Diol-3-One 20-*Acetat E is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.