Description

Barminomycin I CAS NO 108147-17-7 is a specialized anthracycline antibiotic compound of significant interest in pharmaceutical research and development. Its primary value lies in its potent biological activity, which makes it a crucial intermediate and reference standard for the study of novel anti-cancer and antimicrobial agents. This product is essential for research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery, mechanism-of-action studies, and the synthesis of new therapeutic entities.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and building block in the discovery and synthesis of new anthracycline-based chemotherapeutic agents.
• Biochemical Studies: Used to investigate mechanisms of action involving DNA intercalation and topoisomerase II inhibition in cancer cell lines.
• Antimicrobial Research: Employed in studies targeting the development of new antibiotics against resistant bacterial strains.
• Academic Research: A critical tool for universities and research institutes studying the structure-activity relationships (SAR) of natural product derivatives.
• Process Chemistry: Acts as a high-purity intermediate for the scale-up and optimization of synthetic routes for complex bioactive molecules.
• Quality Control & Analytical Standards: Utilized as a certified reference material (CRM) for HPLC, LC-MS, and NMR method development and validation in analytical laboratories.

Basic Information

Product Name	Barminomycin I
CAS No.	108147-17-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Barminomycin I; Antibiotic Barminomycin I; 108147-17-7; (8S,10S)-8-Glycoloyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione (IUPAC); 7H-Tetracene-5,12-dione, 9,10-dihydro-8-glycoloyl-1-methoxy-6,8,11-trihydroxy-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-tetrahydropyranyl]oxy-, (8S,10S)-
EINECS	Contact for details

Quality Control

Every batch of Barminomycin I is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.