Description

Saframycin Ad-1 is a potent ansamycin-class antibiotic compound with significant biological activity. This specialized chemical is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in the discovery of novel anti-infective and anti-cancer agents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block in the synthesis and study of novel antibiotic candidates.
• Biochemical Assay Development: Used as a precise analytical standard to calibrate equipment and validate methods for detecting ansamycin compounds.
• Mechanism of Action Studies: Employed in preclinical research to investigate the biological pathways and targets of ansamycin antibiotics.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and microbiological research.
• High-Purity Intermediates: Acts as a high-grade intermediate for the synthesis of more complex ansamycin derivatives with potential therapeutic applications.

Basic Information

Product Name	Saframycin Ad-1
CAS No.	107140-33-0
Molecular Formula	C29H31N3O7
Molecular Weight	533.57 g/mol
Synonyms	Saframycin AD-1; Antibiotic C-15003PND; NSC 330500; 1,2,3,4-Tetrahydro-8,9-dimethoxy-5-methyl-1,4-epoxy-6H-isoquinolino[2,1-g][1,6]naphthyridine-6,11,14(5H)-trione; (1S,4S)-8,9-Dimethoxy-5-methyl-1,4-epoxy-1,2,3,4-tetrahydro-6H-isoquinolino[2,1-g][1,6]naphthyridine-6,11,14(5H)-trione
EINECS	Contact for details

Quality Control

Our Saframycin Ad-1 is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by comprehensive analytical documentation, including HPLC chromatograms and spectral data (NMR, MS). Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.