Description

11β-Hydroxy-16α-Methyl-6-Methylene-17,20:20,21-Bis(Methylenedioxy)-Pregn-4-En-3-One is a high-purity synthetic steroid intermediate of significant importance in advanced pharmaceutical research and development. Its complex, multi-functional structure makes it a critical building block for the synthesis of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory drug discovery. This compound is essential for R&D laboratories and pharmaceutical manufacturers focused on developing next-generation steroid-based medications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potent corticosteroid analogs and other bioactive steroid molecules.
• Research & Development: Used in academic and industrial R&D settings for structure-activity relationship (SAR) studies to develop new anti-inflammatory and immunomodulatory drugs.
• Reference Standard: Employed as a high-purity analytical reference standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry: Utilized in process development and scale-up activities for the commercial manufacturing of specialty active pharmaceutical ingredients (APIs).
• Biochemical Research: Applied in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	11β-Hydroxy-16α-Methyl-6-Methylene-17,20:20,21-Bis(Methylenedioxy)-Pregn-4-En-3-One
CAS No.	106712-27-0
Molecular Formula	C₂₆H₃₄O₆
Molecular Weight	442.55 g/mol
Synonyms	11β-Hydroxy-16α-methyl-6-methylene-17,20:20,21-bis(methylenedioxy)pregn-4-en-3-one; 6-Methylene Prednisolone 17,20:20,21-Bis(methylenedioxy) Derivative; 11β,16α-Dimethyl-6-methylenepregna-1,4-diene-3,20-dione cyclic 17,20:20,21-bis(acetal); 16α-Methyl-6-methyleneprednisolone 17,20:20,21-bis(methylenedioxy); (11β,16α)-11,21-Dihydroxy-16-methyl-6-methylenepregna-1,4-diene-3,20-dione cyclic 17,20:20,21-bis(acetal)
EINECS	Contact for details

Quality Control

Our 11β-Hydroxy-16α-Methyl-6-Methylene-17,20:20,21-Bis(Methylenedioxy)-Pregn-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting pharmaceutical intermediate standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.