Description

Azinomycin A is a potent, naturally occurring antitumor antibiotic belonging to the azinomycin family. Its unique molecular architecture, featuring an aziridine ring and an epoxide moiety, enables it to function as a highly effective DNA cross-linking agent, making it a compound of significant interest in advanced research. This product is primarily utilized by pharmaceutical R&D teams and academic institutions focused on oncology and molecular biology to investigate novel therapeutic mechanisms and develop next-generation chemotherapeutic agents.

Application

• Anticancer Research: Serves as a critical reference standard and active compound in studies targeting DNA alkylation and interstrand cross-linking for novel oncology therapeutics.
• Biochemical Mechanism Studies: Used to investigate the molecular mechanisms of action of DNA-binding antibiotics and their effects on cell cycle arrest and apoptosis.
• Pharmaceutical Development: Acts as a lead compound or a molecular scaffold in the discovery and structure-activity relationship (SAR) studies of new chemotherapeutic agents.
• Academic Research: Employed in university and institutional labs for fundamental research in chemical biology, medicinal chemistry, and pharmacology.
• Biosynthesis Pathway Analysis: Utilized as a standard in studies exploring the microbial biosynthesis pathways of complex natural products.

Basic Information

Product Name	Azinomycin A
CAS No.	106486-77-5
Molecular Formula	C29H36N4O9
Molecular Weight	584.62 g/mol
Synonyms	Carzinophilin A; Azinomycin B (often used interchangeably in literature); Antibiotic X-5108; [1S-(1R*,2S*,10S*,11R*,12S*,13R*,19aS*)]-2,3,4,6,7,8,9,10,11,12,13,14,15,16,20,20a-Hexadecah-10,13-dihydroxy-12-[(1E)-1-propenyl]-2,6,8,11,14,16-hexamethyl-1,19a-epoxy-19H-1,10-diazacyclooctadeca[2,1-b:7,8-b']diindole-5,18-dione
EINECS	Contact for details

Quality Control

Every batch of Azinomycin A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a dry, cool, and well-ventilated area, away from incompatible materials. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.