Description

Cyanopindolol Hemifumarate is a high-purity, non-selective β-adrenergic receptor antagonist (β-blocker) with intrinsic sympathomimetic activity. This compound is a critical research-grade biochemical used extensively in pharmacological studies to investigate adrenergic receptor function and signaling pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and contract research organizations (CROs) focused on cardiovascular and neurological research.

Application

• Pharmacological Research: A key tool compound for studying β-adrenergic receptor binding, antagonism, and downstream cellular effects.
• Biochemical Assay Development: Used as a reference standard in the development and validation of high-throughput screening (HTS) assays for drug discovery.
• Academic Neuroscience Studies: Employed in experimental models to understand the role of β-blockers in central nervous system function and behavior.
• Cardiovascular Research: Investigated for its effects on heart rate, blood pressure, and vascular tone in preclinical studies.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.
• Metabolic Pathway Investigation: Used to explore the interaction between adrenergic signaling and metabolic processes.

Basic Information

Product Name	Cyanopindolol Hemifumarate
CAS No.	106469-57-2
Molecular Formula	C21H21N3O2 • 0.5C4H4O4
Molecular Weight	379.41 g/mol (free base: 347.41)
Synonyms	Cyanopindolol Hemifumarate Salt; (±)-Cyanopindolol Hemifumarate; (RS)-Cyanopindolol Hemifumarate; 3-(2-Cyano-3-indolyloxy)-2-hydroxypropylaminoethanol Hemifumarate; SDZ CI-959; ICI 118,551 (common reference, though structurally distinct); β-Adrenergic Blocker Cyanopindolol; 4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-2-cyano-1H-indole Hemifumarate
EINECS	Contact for details

Quality Control

Our Cyanopindolol Hemifumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research applications. A detailed Certificate of Analysis (COA) documenting purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.