Description

Falintolol, (Z)- is a specific stereoisomer of the β-adrenergic receptor antagonist (β-blocker) Falintolol, identified by CAS NO 106401-52-9. This compound is of significant interest in pharmaceutical research and development for its potential cardiovascular activity and as a key intermediate in synthetic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly those targeting hypertension, angina, and other related conditions. The compound's defined stereochemistry is crucial for its biological interaction and efficacy.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of advanced β-blocker drug candidates.
• Biochemical Research: Used as a reference standard or active compound in pharmacological studies investigating β-adrenergic receptor mechanisms.
• Preclinical Development: Employed in the formulation and testing stages for new cardiovascular therapeutics.
• Chemical Synthesis: Acts as a specialized intermediate for medicinal chemists exploring structure-activity relationships (SAR) within the β-blocker class.
• Analytical Standard: Utilized in quality control laboratories for method development and validation, including HPLC and LC-MS analysis.

Basic Information

Product Name	Falintolol, (Z)-
CAS No.	106401-52-9
Molecular Formula	C17H26N2O4
Molecular Weight	322.40 g/mol
Synonyms	(Z)-Falintolol; (Z)-1-[4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-3-phenyl-2-propen-1-one; (Z)-1-[4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]-3-phenyl-2-propen-1-one; Falintolol Z-isomer; (Z)-Isomer of Falintolol
EINECS	Contact for details

Quality Control

Our Falintolol, (Z)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of specific impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the results against our stringent in-house specifications. Our commitment ensures material consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.