Description

Itrocinonide is a synthetic corticosteroid belonging to the glucocorticoid class, known for its potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for the development of targeted topical and systemic therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in advanced drug development, particularly for dermatological and inflammatory conditions.

Application

• Pharmaceutical API: Serves as the core active ingredient in the formulation of prescription-strength topical creams, ointments, and lotions for treating severe eczema, psoriasis, and dermatitis.
• Veterinary Medicine: Incorporated into topical preparations for managing inflammatory skin conditions and allergic reactions in animals.
• Clinical Research: Used as a reference standard and investigational compound in pharmacological studies focusing on glucocorticoid receptor activity and anti-inflammatory mechanisms.
• Drug Delivery Systems: A key component in the development of advanced delivery platforms, such as transdermal patches and nano-formulations, aimed at enhancing bioavailability and reducing systemic side effects.

Basic Information

Product Name	Itrocinonide
CAS No.	106033-96-9
Molecular Formula	C28H37FO7
Molecular Weight	504.59 g/mol
Synonyms	Itrocinonide; 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; Fluocinolone Acetonide related compound; Itrocinonidum; Itrocinonida
EINECS	Contact for details

Quality Control

Our Itrocinonide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Specifications typically align with major pharmacopeial guidelines. A detailed Certificate of Analysis (COA), including results for identity, purity, and related substances, is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.