Description

7-o-Ribofuranosyldaunomycinone CAS NO 105444-04-0 is a key anthracycline glycoside derivative, primarily recognized as a critical intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in its structural role as a precursor to potent chemotherapeutic agents, enabling advanced research and development in oncology. This high-purity intermediate is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers focused on developing novel anti-cancer therapeutics and conducting biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced anthracycline-based chemotherapeutic drugs.
• Oncology Research: Used in biochemical and pharmacological research to study structure-activity relationships and develop new anti-cancer agents.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Industrial R&D: Facilitates exploratory synthesis in academic laboratories and industrial R&D departments for novel drug discovery programs.
• Bioconjugation Studies: Utilized in studies aiming to conjugate active pharmaceutical ingredients to targeting molecules or delivery systems.

Basic Information

Product Name	7-o-Ribofuranosyldaunomycinone
CAS No.	105444-04-0
Molecular Formula	C27H29NO10
Molecular Weight	527.52 g/mol
Synonyms	7-O-Ribofuranosyldaunomycinone; Daunomycinone 7-O-ribofuranoside; 7-O-(β-D-Ribofuranosyl)daunomycinone; 4-Demethoxydaunorubicin aglycone riboside; 7-O-β-D-Ribofuranosyldaunomycinone; 7-O-Ribofuranosyl-13-dihydrodaunomycinone; Anthracycline intermediate; Daunorubicin precursor derivative
EINECS	Contact for details

Quality Control

Our 7-o-Ribofuranosyldaunomycinone is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for demanding pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Reddish-orange to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.