Description

6-Fluoro-2-Nitrophenylacetonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both a nitrile and a nitro group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers and liquid crystals with unique electronic or optical properties.
• Dye and Pigment Manufacturing: Intermediate for producing complex, light-fast organic dyes and colorants.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures common in many advanced materials.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular processes.

Basic Information

Item	Details
Product Name	6-Fluoro-2-Nitrophenylacetonitrile
CAS No.	105003-93-8
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	2-(6-Fluoro-2-nitrophenyl)acetonitrile; (6-Fluoro-2-nitrophenyl)acetonitrile; 6-Fluoro-2-nitrobenzyl cyanide; α-Cyano-6-fluoro-2-nitro toluene; 2-Nitro-6-fluorophenylacetonitrile; 105003-93-8; 6-Fluoro-2-nitrobenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Nitrophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.