Description

2-(3-Fluoro-2-Nitrophenyl)Acetonitrile is a versatile and high-purity fluorinated nitrile building block essential for advanced organic synthesis. Its unique molecular structure, featuring both electron-withdrawing nitro and fluoro substituents on the aromatic ring, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials where the nitrile and fluoronitro groups impart specific electronic and physical properties.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags, affinity labels, and other molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	2-(3-Fluoro-2-Nitrophenyl)Acetonitrile
CAS No.	105003-88-1
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	(3-Fluoro-2-nitrophenyl)acetonitrile; 2-Nitro-3-fluorobenzyl cyanide; 3-Fluoro-2-nitrobenzeneacetonitrile; α-Cyano-3-fluoro-2-nitrotoluene; 2-(3-Fluoro-2-nitrophenyl)ethanenitrile; 105003-88-1; 3-Fluoro-2-nitrophenylacetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluoro-2-Nitrophenyl)Acetonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical purity and consistency to meet the exacting requirements of research and process chemistry. A detailed Certificate of Analysis (COA) providing results for identity, purity, and impurity profiles is supplied with each shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent absorption of water vapor from the atmosphere.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.