Description

2-Fluoro-5-Hydroxybenzenecarbonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyano group and a hydroxyl group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorophenol or fluorobenzonitrile moiety.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with tailored properties such as thermal stability, chemical resistance, or specific optical characteristics.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new fluorination chemistry, cross-coupling reactions, and heterocyclic compound synthesis.
• Dye & Pigment Intermediate: Acts as a starting material for the production of specialized dyes and pigments, leveraging the electron-withdrawing nature of the cyano and fluoro groups.

Basic Information

Product Name	2-Fluoro-5-Hydroxybenzenecarbonitrile
CAS No.	104798-53-0
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	5-Cyano-2-fluorophenol; 2-Fluoro-5-hydroxybenzonitrile; 5-Hydroxy-2-fluorobenzonitrile; 2-Fluor-5-hydroxybenzonitril; 2-Fluoro-5-cyanophenol; 5-Fluor-2-hydroxybenzonitril; 2-Fluoro-5-hydroxyphenyl cyanide; 104798-53-0
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Hydroxybenzenecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be hygroscopic; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.