Description

Prednisolone 17-Ethylcarbonate is a key pharmaceutical intermediate and a chemically modified derivative of the corticosteroid prednisolone. This compound is valued for its role in the synthesis of advanced steroid-based therapeutics, offering enhanced stability and specific pharmacokinetic properties. It is primarily required by manufacturers in the pharmaceutical and life sciences sectors for the development and production of anti-inflammatory and immunosuppressant medications.

Application

• Pharmaceutical Intermediate: Critical raw material in the synthesis of advanced corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Development: Used in research and production of medications targeting conditions like arthritis, asthma, and dermatological disorders.
• Immunosuppressant Formulations: Serves as a precursor for drugs used to prevent organ transplant rejection and treat autoimmune diseases.
• Veterinary Medicine: Employed in the formulation of anti-inflammatory treatments for animals.
• Biochemical Research: Used as a reference standard and probe in steroid receptor and metabolic pathway studies.
• Prodrug Synthesis: The ethylcarbonate moiety can be utilized to create prodrugs with modified release profiles.

Basic Information

Product Name	Prednisolone 17-Ethylcarbonate
CAS No.	104286-02-4
Molecular Formula	C₂₄H₃₂O₇
Molecular Weight	432.51 g/mol
Synonyms	Prednisolone 21-Ethyl Carbonate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-Ethyl Carbonate; 17α,21-Dihydroxypregna-1,4-diene-3,11,20-trione 21-Ethyl Carbonate; Prednisolone Ethyl Carbonate; NSC 113927; Ethyl Prednisolone-21-carbonate
EINECS	Contact for details

Quality Control

Our Prednisolone 17-Ethylcarbonate is manufactured and tested under a strict quality management system. We provide material that meets high-purity standards suitable for pharmaceutical R&D and GMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by validated methods (e.g., HPLC) is supplied with each batch to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.