Description

3-Bromo-2,4-Difluoronitrobenzene 98% is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its precise structure, featuring bromo, fluoro, and nitro substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the difluoro and bromo substituents influence bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine atom.
• Nucleophilic Aromatic Substitution: The electron-deficient ring, activated by the nitro and fluoro groups, facilitates substitution reactions for introducing diverse functionalities.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new synthetic routes and compound libraries.

Basic Information

Product Name	3-Bromo-2,4-Difluoronitrobenzene 98%
CAS No.	103977-78-2
Molecular Formula	C6H2BrF2NO2
Molecular Weight	237.99 g/mol
Synonyms	1-Bromo-2,4-difluoro-3-nitrobenzene; 2,4-Difluoro-3-nitrobenzene Bromide; 3-Nitro-2,4-difluorobromobenzene; Benzene, 1-bromo-2,4-difluoro-3-nitro-; 3-Bromo-2,4-difluoro-1-nitrobenzene; 2,4-Difluoro-3-nitro-1-bromobenzene; 3-Bromo-2,4-difluoronitrobenzene; 103977-78-2
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4-Difluoronitrobenzene 98% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.