Description

7-o-(2,6-Dideoxy-2-Fluorotalopyranose)Adriamycinone is a key synthetic intermediate in the development of novel anthracycline-based chemotherapeutic agents. This compound is critical for researchers and manufacturers focused on creating advanced oncology drugs with potentially improved efficacy and reduced side-effect profiles. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of next-generation fluorinated anthracycline derivatives for cancer therapy.
• Oncology Drug Discovery: Used in medicinal chemistry research to develop and evaluate new chemotherapeutic candidates targeting various cancers.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of DNA-intercalating agents and topoisomerase II inhibitors.
• Fine Chemical Synthesis: A specialized reagent for the custom synthesis of complex, fluorinated carbohydrate-conjugated molecules in contract manufacturing.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	7-o-(2,6-Dideoxy-2-Fluorotalopyranose)Adriamycinone
CAS No.	103930-51-4
Molecular Formula	C₂₇H₂₉FNO₁₀
Molecular Weight	546.52 g/mol
Synonyms	7-O-(2,6-Dideoxy-2-fluoro-α-L-talopyranosyl)adriamycinone; 2'-Fluoro-4'-epidoxorubicin aglycone; 7-O-(2,6-Dideoxy-2-fluoro-α-L-talopyranosyl)doxorubicinone; Fluorinated doxorubicin intermediate; 7-O-(2-Deoxy-2-fluoro-α-L-talopyranosyl)adriamycinone; 103930-51-4; 7-O-(2,6-Dideoxy-2-fluoro-α-L-talopyranosyl)-13-dihydrocarminomycinone
EINECS	Contact for details

Quality Control

Our 7-o-(2,6-Dideoxy-2-Fluorotalopyranose)Adriamycinone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.