Description

(7R)-10α-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-8-Ethyl-7,8,9,10-Tetrahydro-1,6,7β,8α,11-Pentahydroxy-5,12-Naphthacenedione is a complex, high-purity anthracycline derivative of significant interest in advanced pharmaceutical research and development. Its intricate molecular structure, featuring a glycosylated naphthacenedione core, makes it a critical intermediate for synthesizing novel therapeutic agents. This compound is primarily sought by research institutions and pharmaceutical companies engaged in oncology and antibiotic drug discovery. The precise stereochemistry and functional groups are essential for biological activity, demanding suppliers with expertise in handling sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Oncology Research: Used in preclinical studies to develop new anti-cancer drugs targeting DNA intercalation and topoisomerase inhibition.
• Antibiotic Development: Investigated for its potential as a precursor in creating new classes of antibiotics with modified activity profiles.
• Biochemical Research: Employed as a standard or reference compound in studies of drug-receptor interactions and mechanism of action.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
• Academic Research: Supports chemical and pharmacological studies in university and institutional laboratories focusing on natural product derivatives.

Basic Information

Item	Details
Product Name	(7R)-10α-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-8-Ethyl-7,8,9,10-Tetrahydro-1,6,7β,8α,11-Pentahydroxy-5,12-Naphthacenedione
CAS No.	103782-06-5
Molecular Formula	C25H29NO11
Molecular Weight	519.50 g/mol
Synonyms	8-Ethyl-10α-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,7β,8α,11-pentahydroxy-5,12-naphthacenedione; 10-Deoxydaunorubicin aglycone derivative; 8-Ethyl-10-O-(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)-1,6,7,8,9,10,11,12-octahydrotetracene-5,12-dione; Anthracycline derivative intermediate; Daunosaminyl naphthacenedione
EINECS	Contact for details

Quality Control

Every batch of our (7R)-10α-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-8-Ethyl-7,8,9,10-Tetrahydro-1,6,7β,8α,11-Pentahydroxy-5,12-Naphthacenedione is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, related substances, and residual solvents. Our quality protocols are designed to support regulatory filings and ensure reliable, reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.