Description

Pregna-1,4-Diene-3,20-Dione, 9,11-Epoxy-17,21-Dihydroxy-6,16-Dimethyl-, (6α,9β,11β,16α)- CAS NO 103374-59-0 is a high-purity synthetic steroid derivative with a complex, multi-functional molecular structure. This compound is a critical advanced pharmaceutical intermediate (API) valued for its precise stereochemistry and functional groups, which serve as key building blocks in complex organic syntheses. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly within the steroid and hormone research fields.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel corticosteroid analogs and other biologically active steroid molecules.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) research, and the discovery of new drug candidates.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using techniques like HPLC and LC-MS.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Item	Details
Product Name	Pregna-1,4-Diene-3,20-Dione, 9,11-Epoxy-17,21-Dihydroxy-6,16-Dimethyl-, (6α,9β,11β,16α)-
CAS No.	103374-59-0
Molecular Formula	C23H30O5
Molecular Weight	386.49 g/mol
Synonyms	9,11-Epoxy-17,21-dihydroxy-6,16-dimethylpregna-1,4-diene-3,20-dione; (6α,9β,11β,16α)-9,11-Epoxy-17,21-dihydroxy-6,16-dimethylpregna-1,4-diene-3,20-dione; 6α,9β,11β,16α-Tetrahydroxy-6,16-dimethylpregna-1,4-diene-3,20-dione 9,11-acetonide; A synthetic corticosteroid intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 9,11-Epoxy-17,21-Dihydroxy-6,16-Dimethyl-, (6α,9β,11β,16α)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.