Description

3-Chloro-4-Fluoro-5-Nitrobenzotrifluoride is a high-value, multi-functional aromatic intermediate characterized by its unique combination of halogen and nitro substituents on a trifluoromethylated benzene ring. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, crop protection, and pharmaceutical industries for creating novel active ingredients and specialty materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and halogen groups.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, particularly in scaffolds requiring fluorinated motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Synthesis: Employed in the production of complex, high-performance colorants and imaging agents.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Liquid Crystal & OLED Materials: A potential intermediate for electronic chemicals used in display and lighting technologies.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-Nitrobenzotrifluoride
CAS No.	101646-02-0
Molecular Formula	C7H2ClF4NO2
Molecular Weight	243.54 g/mol
Synonyms	1-Chloro-2-fluoro-3-nitro-5-(trifluoromethyl)benzene; 2-Fluoro-3-nitro-5-(trifluoromethyl)chlorobenzene; 3-Chloro-4-fluoro-5-nitro-α,α,α-trifluorotoluene; Benzene, 1-chloro-2-fluoro-3-nitro-5-(trifluoromethyl)-; 5-Trifluoromethyl-3-chloro-4-fluoronitrobenzene; 3-Chloro-4-fluoro-5-nitrobenzotrifluoride; 3-Chloro-4-fluoro-5-nitro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-5-Nitrobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications from HPLC, GC, and NMR are provided to guarantee traceability and batch-to-batch reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.