Description

17,21-Dihydroxypregn-4-Ene-3,20-Dione 17-Acetate is a high-purity steroid derivative and a key intermediate in the synthesis of various pharmaceutical compounds. This compound is valued for its specific molecular structure, which serves as a crucial building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in steroid chemistry and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of corticosteroids and other steroidal drugs.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and developing new therapeutic agents.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules with specific biological activity in custom synthesis projects.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling in pharmaceutical analysis.

Basic Information

Product Name	17,21-Dihydroxypregn-4-Ene-3,20-Dione 17-Acetate
CAS No.	19357-45-0
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	11-Deoxycortisol 21-acetate; 17-Hydroxycortexone 21-acetate; 17α,21-Dihydroxypregn-4-ene-3,20-dione 21-acetate; Reichstein's Substance S 21-acetate; 11-Deoxycortisol acetate; Cortodoxone 21-acetate; Pregn-4-ene-17α,21-diol-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxypregn-4-Ene-3,20-Dione 17-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.