Description

16-.Alpha., 17-Dihydroxy-6-.Alpha.-Methylpregn-4-Ene-3,20-Dione, Cycli C Acetal With Acetone CAS NO 19304-29-1 is a high-purity synthetic steroid derivative, also known as 6α-Methylprednisolone 16,17-Acetonide. This compound is a key pharmaceutical intermediate valued for its potent anti-inflammatory and immunosuppressive properties. It is primarily required by manufacturers in the pharmaceutical and fine chemical industries for the synthesis of advanced corticosteroid APIs and research into novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical raw material for the synthesis of potent corticosteroid active pharmaceutical ingredients (APIs) like methylprednisolone aceponate.
• Anti-inflammatory Drug Research: Used in R&D for developing new topical and systemic anti-inflammatory medications.
• Immunosuppressant Synthesis: Serves as a precursor in manufacturing drugs designed to modulate immune system responses.
• Dermatological Preparations: Found in the production chain for creams and ointments targeting eczema, psoriasis, and other skin conditions.
• Veterinary Medicine: Employed in formulating anti-inflammatory treatments for animals.
• Reference Standard: Used as an analytical standard in quality control laboratories for HPLC and other chromatographic methods.
• Biochemical Research: A tool compound for studying glucocorticoid receptor interactions and steroid metabolism pathways.

Basic Information

Product Name	16-.Alpha., 17-Dihydroxy-6-.Alpha.-Methylpregn-4-Ene-3,20-Dione, Cycli C Acetal With Acetone
CAS No.	19304-29-1
Molecular Formula	C25H36O5
Molecular Weight	416.55 g/mol
Synonyms	6α-Methylprednisolone 16,17-Acetonide; 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione cyclic 16,17-acetal with acetone; Methylprednisolone Aceponate Intermediate; 6α-Methylprednisolone Acetonide; (6α,11β)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 6-Methylprednisolone 16,17-acetonide; 16α,17α-Isopropylidenedioxy-6α-methylpregna-4-ene-3,11,20-trione (deprotected form reference); U-8471
EINECS	Contact for details

Quality Control

Our 16-.Alpha., 17-Dihydroxy-6-.Alpha.-Methylpregn-4-Ene-3,20-Dione, Cycli C Acetal With Acetone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.