Description

17β-(Acetyloxy)-6β-Fluoroestr-4-En-3-One is a high-purity synthetic steroid derivative, also known by its CAS number 18119-95-4. This compound is valued for its role as a critical pharmaceutical intermediate in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid and other steroidal APIs.
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-based drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control testing in laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroid drugs.

Basic Information

Product Name	17β-(Acetyloxy)-6β-Fluoroestr-4-En-3-One
CAS No.	18119-95-4
Molecular Formula	C22H29FO3
Molecular Weight	360.46 g/mol
Synonyms	6β-Fluoro-17β-acetoxyandrost-4-en-3-one; 6β-Fluoro-17β-hydroxy-4-androsten-3-one 17-acetate; 6β-Fluoro-17β-acetoxy-4-androsten-3-one; Fludrocortisone Acetate Intermediate; 6-Fluoro-17α-acetoxyandrost-4-en-3-one (isomeric); 17β-Acetoxy-6β-fluoroandrost-4-en-3-one
EINECS	Contact for details

Quality Control

Our 17β-(Acetyloxy)-6β-Fluoroestr-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.