Description

16α,17-Epoxy-3',3'-Difluoro-6,7β-Dihydro-6β,16-Dimethyl-3'H-Cyclopropa[6,7]Pregna-4,6-Diene-3,20-Dione is a high-purity synthetic steroid derivative with a complex, modified pregnane backbone. This compound is of significant value in advanced pharmaceutical research and development, particularly for its potential as a key intermediate in the synthesis of novel therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing steroidal drugs, hormone modulators, and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial labs for studying structure-activity relationships (SAR) in steroid chemistry.
• Hormone Analog Development: Serves as a precursor for creating modified glucocorticoid or progestin analogs with targeted biological activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies investigating steroid receptor binding and metabolic pathways.

Basic Information

Product Name	16α,17-Epoxy-3',3'-Difluoro-6,7β-Dihydro-6β,16-Dimethyl-3'H-Cyclopropa[6,7]Pregna-4,6-Diene-3,20-Dione
CAS No.	18069-06-2
Molecular Formula	C₂₄H₂₈F₂O₄
Molecular Weight	418.48 g/mol
Synonyms	16α,17α-Epoxy-3,3-difluoro-6,7-dihydro-6β,16-dimethyl-3'H-cyclopropa[6,7]pregna-4,6-diene-3,20-dione; 16α,17α-Epoxy-3,3-difluoro-6,7-dihydro-6β,16-dimethyl-3'H-cyclopropa[6,7]pregna-4,6-diene-3,20-dione; 16α,17α-Epoxy-3,3-difluoro-6,7-dihydro-6β,16-dimethyl-3'H-cyclopropa[6,7]pregna-4,6-diene-3,20-dione (CAS 18069-06-2); Difluorinated Cyclopropapregnadienedione Derivative; 16α,17α-Epoxy-3,3-difluoro-6β,16-dimethyl-3'H-cyclopropa[6,7]pregna-4,6-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 16α,17-Epoxy-3',3'-Difluoro-6,7β-Dihydro-6β,16-Dimethyl-3'H-Cyclopropa[6,7]Pregna-4,6-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.