Description

4-Chloro-2-Methyl-3-Nitrobenzotrifluoride is a versatile halogenated nitroaromatic compound featuring a trifluoromethyl group, making it a valuable synthetic intermediate. Its unique structure provides reactivity at multiple sites, enabling its use in the construction of complex molecules for advanced applications. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and pigments where the nitro and chloro groups are essential for color development and fastness.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures common in many functional molecules.

Basic Information

Product Name	4-Chloro-2-Methyl-3-Nitrobenzotrifluoride
CAS No.	18018-35-4
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	3-Nitro-4-chloro-2-methylbenzotrifluoride; 4-Chloro-2-methyl-3-nitro-α,α,α-trifluorotoluene; 1-Chloro-4-methyl-2-nitro-5-(trifluoromethyl)benzene; 2-Methyl-4-chloro-3-nitrobenzotrifluoride; 4-Chloro-2-methyl-3-nitro-α,α,α-trifluorotoluene; Benzene, 1-chloro-4-methyl-2-nitro-5-(trifluoromethyl)-; 4-Chloro-2-methyl-3-nitrobenzotrifluoride (CAS 18018-35-4)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-3-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.