Description

3,12β-Dihydroxy-1,3,5(10)-Estratrien-17-One CAS NO 17736-14-0 is a high-purity steroid derivative, specifically a dihydroxy estratriene, serving as a critical intermediate in advanced pharmaceutical synthesis. Its precise molecular structure makes it an essential building block for the research and development of novel therapeutic agents, particularly in the field of endocrinology. This compound is primarily targeted at pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and hormone-related drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of specialized steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in metabolic pathway studies and the development of diagnostic assays related to hormonal function.
• Fine Chemical Synthesis: Utilized for the custom synthesis of more complex, target-specific steroid molecules for clinical research.

Basic Information

Product Name	3,12β-Dihydroxy-1,3,5(10)-Estratrien-17-One
CAS No.	17736-14-0
Molecular Formula	C₁₈H₂₄O₃
Molecular Weight	288.38 g/mol
Synonyms	3,12β-Dihydroxyestra-1,3,5(10)-trien-17-one; 3,12β-Dihydroxy-1,3,5(10)-estratrien-17-one; 12β-Hydroxy-3-hydroxyestra-1,3,5(10)-trien-17-one; Estra-1,3,5(10)-triene-3,12β-diol-17-one; 17-Oxoestra-1,3,5(10)-triene-3,12β-diol
EINECS	Contact for details

Quality Control

Our 3,12β-Dihydroxy-1,3,5(10)-Estratrien-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.