Description

4,6-Difluoro-Isophthalonitrile is a high-value aromatic nitrile derivative distinguished by its strategic fluorine substitution. This compound serves as a critical advanced intermediate for synthesizing complex molecules, offering unique reactivity and electronic properties. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organic synthesis.
• Polymer and Material Science: Intermediate for manufacturing high-performance polymers, liquid crystals, and electronic materials requiring specific dielectric or optical properties.
• Organic Light-Emitting Diodes (OLEDs): Potential precursor in the development of electron-transport or emissive layer materials for display and lighting technologies.
• Research & Development: A versatile scaffold in medicinal and synthetic chemistry research for exploring new chemical entities and reaction pathways.

Basic Information

Item	Details
Product Name	4,6-Difluoro-Isophthalonitrile
CAS No.	17654-70-5
Molecular Formula	C8H2F2N2
Molecular Weight	164.11 g/mol
Synonyms	1,3-Dicyano-2,4-difluorobenzene; 2,4-Difluoroisophthalonitrile; 4,6-Difluorobenzene-1,3-dicarbonitrile; Isophthalonitrile, 4,6-difluoro-; 4,6-Difluoro-1,3-benzenedicarbonitrile; 4,6-Difluoroisophthalonitrile; DFIPN
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-Isophthalonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, NMR, and other relevant methods. Our quality commitment aligns with cGMP principles where applicable for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.