Description

2,4,5-Trifluoroiodobenzene is a high-value, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique combination of fluorine and iodine substituents makes it a critical reagent for introducing fluorinated aryl groups into complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and as a precursor to other fluorinated intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluorinated phenyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Cross-Coupling Reactions: Serves as an excellent electrophile in palladium-catalyzed reactions such as Suzuki, Sonogashira, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Liquid Crystal & OLED Materials: Employed in the research and production of fluorinated organic electronic materials for displays and lighting.
• Fluorinated Ligand Preparation: Used to synthesize specialized fluorinated ligands for catalysis and coordination chemistry.
• Positron Emission Tomography (PET) Tracer Development: Acts as a potential precursor for radiolabeling with fluorine-18 in diagnostic imaging agent research.

Basic Information

Product Name	2,4,5-Trifluoroiodobenzene
CAS No.	17533-08-3
Molecular Formula	C6H2F3I
Molecular Weight	273.98 g/mol
Synonyms	1-Iodo-2,4,5-trifluorobenzene; 2,4,5-Trifluoro-1-iodobenzene; Benzene, 2,4,5-trifluoro-1-iodo-; 2,4,5-Trifluorophenyl iodide; (2,4,5-Trifluorophenyl)iodide
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoroiodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.