Description

2-Fluoro-5-Nitrobenzonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a fluorine atom, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and polarizable nature.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the nitro and cyano groups contribute to color and fastness properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create biaryl and other complex structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2-Fluoro-5-Nitrobenzonitrile
CAS No.	17417-09-3
Molecular Formula	C7H3FN2O2
Molecular Weight	166.11 g/mol
Synonyms	5-Nitro-2-fluorobenzonitrile; 2-Fluoro-5-nitrobenzenecarbonitrile; Benzonitrile, 2-fluoro-5-nitro-; 2-Fluoro-5-nitro-benzonitril; 5-Nitro-2-fluorobenznitril; 17417-09-3; 2-Fluoro-5-nitrobenzonitril; 2-Fluor-5-nitro-benzonitril
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.