Description

16-Methyl-3,17-Dihydroxy-5Alpha-Pregnane-20-One-3-Acetate is a high-purity steroid derivative and a key synthetic intermediate in the production of specialized pharmaceutical compounds. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is essential for research and development laboratories, as well as manufacturers in the pharmaceutical and fine chemical sectors, who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of steroidal drugs, including corticosteroids and other hormone-related therapeutics.
• Research & Development: Used in academic and industrial R&D for studying steroid metabolism, receptor interactions, and developing new bioactive molecules.
• Reference Standard: Serves as a certified reference material (CRM) or analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex, value-added steroid analogs for various applications.

Basic Information

Product Name	16-Methyl-3,17-Dihydroxy-5Alpha-Pregnane-20-One-3-Acetate
CAS No.	16980-67-9
Molecular Formula	C₂₄H₃₈O₄
Molecular Weight	390.56 g/mol
Synonyms	16-Methyl-3β,17α-Dihydroxy-5α-pregnan-20-one 3-Acetate; 3β,17α-Dihydroxy-16β-methyl-5α-pregnan-20-one 3-Acetate; 16β-Methyl-3β,17α-dihydroxy-5α-pregnan-20-one 3-acetate; 5α-Pregnane-3β,17α-diol-20-one, 16-methyl-, 3-acetate; NSC 113986; 16-Methyl Steroid Intermediate
EINECS	Contact for details

Quality Control

Our 16-Methyl-3,17-Dihydroxy-5Alpha-Pregnane-20-One-3-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.