Description

n-Methyl-n-[(20S)-4,4,14-Trimethyl-3β-(Methylamino)-9β,19-Cyclo-5α-Pregnan-20-Yl]Acetamide is a high-purity, steroidal alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting specific biological pathways. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs. The product, identified by CAS NO 16974-77-9, is supplied under stringent quality control to ensure reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel steroidal drugs and bioactive molecules.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Investigated for its interaction with specific enzymes or receptors in pharmacological studies.
• Process Development: Utilized in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	n-Methyl-n-[(20S)-4,4,14-Trimethyl-3β-(Methylamino)-9β,19-Cyclo-5α-Pregnan-20-Yl]Acetamide
CAS No.	16974-77-9
Molecular Formula	C₂₈H₄₈N₂O
Molecular Weight	428.70 g/mol
Synonyms	20S-Acetamido-4,4,14-trimethyl-3β-(methylamino)-9β,19-cyclo-5α-pregnane; 3β-(Methylamino)-9β,19-cyclo-5α-pregnane-20S-acetamide, 4,4,14-trimethyl-; (20S)-N-Methyl-N-[4,4,14-trimethyl-3β-(methylamino)-9β,19-cyclo-5α-pregnan-20-yl]acetamide; 3β-Methylamino-9β,19-cyclo-5α-lanost-20S-yl methylacetamide; A steroidal alkaloid derivative; Conessine derivative; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our n-Methyl-n-[(20S)-4,4,14-Trimethyl-3β-(Methylamino)-9β,19-Cyclo-5α-Pregnan-20-Yl]Acetamide is manufactured and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support development projects requiring compliance with GMP or ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to ensure maximum stability. Keep container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.